ADH1B Antibody
Mouse Monoclonal
Catalog number: 65033-1-Ig
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse; other species not tested. |
| Cited species | |
| Positive WB detected in | Human liver |
| Positive IHC detected in | Liver cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Human liver were subjected to SDS PAGE followed by western blot with 65033-1-Ig(ADH1B Antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded Liver cancer using 65033-1-Ig(ADH1B Antibody) at Dilution 1:100
Product Information
| Source | Mouse | Purification method | Protein G purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Recombinant Protein | Full name | alcohol dehydrogenase 1B (class I), beta polypeptide |
|
Calculated molecular weight |
375aa,40kd |
Observed molecular
weight |
|
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GenBank accession number |
BC033009 | Gene ID (NCBI) | 125 |
| Gene symbol | ADH1B | Synonyms | ADH2; DKFZp686C06125 |
Background
The ADH1B gene encodes the beta subunit of class I alcohol dehydrogenase (ADH), an enzyme that catalyzes the rate-limiting step for ethanol metabolism: the oxidation of alcohol to acetaldehyde. Class 1 ADH is a homo- or heterodimeric molecule, formed by the association of 3 types of class I ADH subunits, alpha (ADH1A), beta, and gamma(ADH1C). ADH1B is also named as ADH2 and belongs to the zinc-containing alcohol dehydrogenase family. This protein can exsit as a homodimer(PMID:19365573). This antibody is specific to ADH1B. |
