AURKB Antibody
Mouse Monoclonal
Catalog number: 65031-1-Ig
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse; other species not tested. |
| Cited species | |
| Positive WB detected in | SK-N-SH cells |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
SK-N-SH cells were subjected to SDS PAGE followed by western blot with 65031-1-Ig(AURKB Antibody) at dilution of 1:1000
Product Information
| Source | Mouse | Purification method | Protein A purification |
| Isotype | IgG1 | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Recombinant Protein | Full name | aurora kinase B |
|
Calculated molecular weight |
39.2kd |
Observed molecular
weight |
|
|
GenBank accession number |
BC013300 | Gene ID (NCBI) | 9212 |
| Gene symbol | AURKB | Synonyms | AIK2; AIM-1; AIM1; ARK2; AurB; IPL1; STK12; STK5 |
Background
Aurora kinase B(AURKB) is also named as AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 and belongs to the Aurora subfamily. Aurora kinase B is a chromosomal passenger serine/threonine protein kinase that regulates accurate chromosomal segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachments, and regulation of the mitotic checkpoint(PMID:18311747). Expression levels of AURKB are increased in the anaplastic thyroid carcinoma cell lines ARO, Cal 62, and KAT-4(PMID:15562011). This antibody is specific to AURKB. |
