CXCR4 Antibody
Rabbit Polyclonal
Catalog number: 16162-1-AP
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Applications
| Tested applications | ELISA |
| Cited applications | |
| Species specificity | human; other species not tested. |
| Cited species |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | chemokine (C-X-C motif) receptor 4 |
|
Calculated molecular weight |
40kd |
Observed molecular
weight |
|
|
GenBank accession number |
NM_001008540 | Gene ID (NCBI) | 7852 |
| Gene symbol | CXCR4 | Synonyms | CD184; D2S201E; FB22; HM89; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM |
Background
The chemokine receptor CXCR4, a 7-transmembrane protein on cell surface, acts with the CD4 protein to support HIV entry into cells. CXCR4 is highly expressed in brain and heart, white blood cells, vascular endothelial cells, and umbilical cord endothelial cells. Lots of CXCR4 isoforms have been reported: 47, 50, 62, and 98-102 kDa. The 62-kDa CXCR4 is predominantly ubiquitinated and6 preferentially associated with CD4. |
