ERO1LB Antibody
Rabbit Polyclonal
Catalog number: 11261-2-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | HeLa cells, human placenta tissue |
| Positive IHC detected in | human pancreas cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HeLa cells were subjected to SDS PAGE followed by western blot with 11261-2-AP(ERO1LB Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human pancreas cancer using 11261-2-AP(ERO1LB Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ERO1LB fusion protein ag1776 | Full name | ERO1-like beta (S. cerevisiae) |
|
Calculated molecular weight |
54kd |
Observed molecular
weight |
40~50kd |
|
GenBank accession number |
BC032823 | Gene ID (NCBI) | 56605 |
| Gene symbol | ERO1LB | Synonyms |
Background
Endoplasmic reticulum oxidoreductases (Eros) are essential for the formation of disulfide bonds. Mammals express two related Ero proteins, Ero1L alpha and Ero1L beta. The two homologous proteins can form homodimers and mixed heterodimers. ERO1-Lα and -β are highly expressed in organs with a high demand for secretion, consistent with their roles in oxidative folding of ER proteins.This antibosy is specific to ERO1LB. |
