GMFB Antibody
Mouse Monoclonal
Catalog number: 60062-1-Ig
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Applications
| Tested applications | ELISA, WB, IF |
| Cited applications | |
| Species specificity | human, mouse; other species not tested. |
| Cited species | |
| Positive WB detected in | Human heart |
| Positive IF detected in | MCF-7 cells |
| Recommended dilution | WB: 1:200-1:2000 IF: 1:20-1:50 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Human heart were subjected to SDS PAGE followed by western blot with 60062-1-Ig(GMFB Antibody) at dilution of 1:500
Immunofluorescent analysis of MCF-7 cells, using GMFB antibody 60062-1-lg at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red).
Product Information
| Source | Mouse | Purification method | Caprylic acid/ammonium sulfate precipitation |
| Isotype | IgG1 | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | GMFB fusion protein ag1104 | Full name | glia maturation factor, beta |
|
Calculated molecular weight |
17kd |
Observed molecular
weight |
17kd |
|
GenBank accession number |
BC005359 | Gene ID (NCBI) | 2764 |
| Gene symbol | GMFB | Synonyms | GMF |
Background
GMFB, Glia maturation factor beta, is a nerve growth factor implicated in nervous system development. It was reported that GMF-beta promotes the phenotypic expression of glia and neurons and inhibits the proliferation of their respective tumors in culture cells. GMF-beta protein is specific to the brain where it is expressed in glial cells (mainly astrocytes) and insome neurons. Higher levels of GMFB were found in the central nervous system, except for the spinal cord, and in thymus and colon. |
