NARFL-Specific Antibody
Rabbit Polyclonal
Catalog number: 20209-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | HEK-293 cells |
| Positive IHC detected in | human kidney |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with 20209-1-AP(NARFL-Specific Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using 20209-1-AP(NARFL-Specific Antibody) at Dilution 1:100 (under 40x lens)
Immunohistochemistry of paraffin-embedded human kidney using 20209-1-AP(NARFL-Specific Antibody) at Dilution 1:100 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | nuclear prelamin A recognition factor-like |
|
Calculated molecular weight |
53kd |
Observed molecular
weight |
26-28kd |
|
GenBank accession number |
NM_022493 | Gene ID (NCBI) | 64428 |
| Gene symbol | NARFL | Synonyms | FLJ21988; HPRN; IOP1; LET1L; PRN |
Background
NARFL, also named as PRN and IOP1, belongs to the NARF family. NAFL is a component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. It is required for maturation of extramitochondrial Fe/S proteins. It seems to negatively regulate the level of HIF1A expression, although this effect could be indirect. [18270200], [16956324] The antibody is specific to NARFL. |
