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  • KD/KO Validated

BMP2 Polyclonal antibody

BMP2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (4)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 18933-1-AP

Synonyms

BMP 2, BMP 2A, BMP2, BMP-2, BMP2A, bone morphogenetic protein 2, Bone morphogenetic protein 2A



Tested Applications

Positive WB detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 18933-1-AP is BMP2 Fusion Protein expressed in E. coli.

Tested Reactivity human
Cited Reactivityhuman, mouse, rat, sheep, hamster
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen BMP2 fusion protein Ag13501
Full Name bone morphogenetic protein 2
Calculated Molecular Weight 396 aa, 44 kDa
GenBank Accession NumberBC069214
Gene Symbol BMP2
Gene ID (NCBI) 650
RRIDAB_10641999
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

Protocols

Product Specific Protocols
WB protocol for BMP2 antibody 18933-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratWB,IHC

Biomaterials

Guided bone regeneration is promoted by the molecular events in the membrane compartment.

Authors - Alberto Turri
humanWB

Biomed Pharmacother

Bacitracin promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by stimulating the bone morphogenetic protein-2/Smad axis.

Authors - Hui Li
  • KD Validated
humanWB

Carbohydr Polym

A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4.

Authors - Wucheng Wang
ratWB,IHC

Int J Nanomedicine

The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.

Authors - Guilan Zhang
ratWB

Arterioscler Thromb Vasc Biol

Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.

Authors - Yun Zhou
ratWB,IHC

Antioxid Redox Signal

Role of Nox4 in high calcium-induced renal oxidative stress damage and crystal deposition.

Authors - Yang Xun