Arp5/ACTR5 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 21505-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 38 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse cerebellum tissue, HEK-293 cells, human skeletal muscle tissue, mouse heart tissue, mouse ovary tissue

Positive IP detected in:
HEK-293 cells

Positive IF detected in:
A549 cells, HepG2 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ARP5 actin-related protein 5 homolog (yeast)

Calculated molecular weight:
607aa,68 kDa

Observed molecular weight:
68 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ACTR5

Synonyms
Actin related protein 5, ACTR5, Arp5, hARP5, Sarcoma antigen NY SAR 16
Background

Arp5 is a member of nuclear actin-related proteins (ARPs) that function as components of the chromatin- remodeling complex. Recently study reported that Arp5 regulates smooth muscle cell differentiation through interaction with myocardin (Myocd). Arp5 has been identified as negative regulator of Myocd, suppressing Myocd activity in the nucleus through tightly binding with Myocd RPEL motifs. Alternative splicing results in two variants of Arp5: a broadly expressed arp5-common, and a smooth muscle restricted arp5-sm. Expression of Arp5-sm protein is strongly suppressed in well-differentiated smooth muscle cells by partial messenger RNA decay and translational suppression. (24567363)


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