Angiotensinogen Polyclonal antibody
Angiotensin Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
Cat no : 18303-1-AP
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
18303-1-AP targets Angiotensin in ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide |
Full Name | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
Calculated Molecular Weight | 53 kDa |
GenBank Accession Number | BC011519 |
Gene Symbol | AGT |
Gene ID (NCBI) | 183 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Angiostatin is a part gene (34-43aa) of Angiotensinogen (Serpin A8, 485aa). In response to lowered blood pressure, the enzyme renin cleaves angiotensin-1 (34-43aa) from angiotensinogen. ACE (angiotensin converting enzyme) then removes a dipeptide to yield the physiologically active peptide angiotensin-2 (34-41aa), the most potent pressor substance known, which helps regulate volume and mineral balance of body fluids. Angiotensin-3 (35-41aa) stimulates aldosterone release.