Angiotensinogen Polyclonal antibody

Angiotensin Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

ELISA

Conjugate

Unconjugated

Cat no : 18303-1-AP

Synonyms

AGT, Ang I Angiotensin 2, Ang II Angiotensin 3, Ang III, Angiotensin, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, ANHU, Des Asp[1] angiotensin II, Serpin A8, SERPINA8



Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

18303-1-AP targets Angiotensin in ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Calculated Molecular Weight 53 kDa
GenBank Accession NumberBC011519
Gene Symbol AGT
Gene ID (NCBI) 183
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Angiostatin is a part gene (34-43aa) of Angiotensinogen (Serpin A8, 485aa). In response to lowered blood pressure, the enzyme renin cleaves angiotensin-1 (34-43aa) from angiotensinogen. ACE (angiotensin converting enzyme) then removes a dipeptide to yield the physiologically active peptide angiotensin-2 (34-41aa), the most potent pressor substance known, which helps regulate volume and mineral balance of body fluids. Angiotensin-3 (35-41aa) stimulates aldosterone release.