ARF6 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18119-1-AP

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Freight/Packing

Con: 36 μg/150 μl

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Tested Applications

Applications:
ELISA, IHC
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ADP-ribosylation factor 6

Calculated molecular weight:
20 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARF6

Synonyms
ADP ribosylation factor 6, ARF6, DKFZp564M0264
Background

ADP-ribosylation factors (ARFs) are members of the ARF family of GTP-binding proteins of the Ras superfamily, with 20kda protein size. ARFs bind and regulate GTP/GDP cycle by alternating between the active GTP-bound and inactive GDP-bound conformations. ARF family proteins are essential and ubiquitous in eukaryotes. Six highly conserved members of the family have been identified in mammalian cells. They function in vesicular traffic and actin remodelling and other bioprocesses in cells. The ARF6 is one of best identified ARFs It is present at the plasma membrane and to some extent on endosomal membranes where it regulates the flow of trafficking into and out of the cell and the actin cytoskeleton. (PMID: 7759471, PMID: 16042562). This antibody can bind ARFs for the close sequences.


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