ARHGEF4 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 55213-1-AP

Featured Product KD/KO validated

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Con: 55 μg/150 μl

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Species specificity:
human, mouse, human; mouse

Positive WB detected in:
mouse brain tissue, multi-cells/tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human brain tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
Rho guanine nucleotide exchange factor (GEF) 4

Calculated molecular weight:
79 kDa

Observed molecular weight:
72 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARHGEF4

Synonyms
ARHGEF4, ASEF, ASEF1, GEF4, KIAA1112, STM6
Background

ARHGEF4, also named as KIAA1112 and Asef, acts as guanine nucleotide exchange factor (GEF) for RhoA and RAC1 GTPases. Binding of APC, ARHGEF4 may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion.(PMID: 10873612). This antibody is specific to ARHGEF4.


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