BBS5 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66136-1-Ig |CloneNo.: 4G8E12

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Con: 108 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
human brain tissue

Positive IHC detected in:
mouse kidney tissue, mouse kidney tissue, mouse testis tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
Bardet-Biedl syndrome 5

Calculated molecular weight:
39 kDa

Observed molecular weight:
39 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BBS5

Synonyms
Bardet Biedl syndrome 5, BBS5
Background

BBS5 encodes a protein that has been directly linked to Bardet-Biedl syndrome. Bardet-Biedl syndrome (BBS) is an autosomal recessive condition characterised by rod-cone dystrophy, postaxial polydactyly, central obesity, mental retardation, hypogonadism, and renal dysfunction. Other associated clinical findings in BBS patients include diabetes, hypertension and congenital heart defects. BBS expression varies both within and between families and diagnosis is often difficult. Experimentation in non-human eukaryotes suggests that BBS5 is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized.


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