BCL10 Monoclonal antibody
BCL10 Monoclonal Antibody for IHC, WB,ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse
Applications
WB, IHC,ELISA
Conjugate
Unconjugated
Cat no : 65014-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | MCF7 cells |
Positive IHC detected in | Breast cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
65014-1-Ig targets BCL10 in WB, IHC,ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Recombinant Protein |
Full Name | B-cell CLL/lymphoma 10 |
Calculated Molecular Weight | 233 aa, 26 kDa |
Observed Molecular Weight | 32 kDa |
GenBank Accession Number | BC053617 |
Gene Symbol | BCL10 |
Gene ID (NCBI) | 8915 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at 2-8°C. 20ul sizes contain 0.1% BSA. |
Background Information
The gene encoding BCL10 was identified by its recurrent translocation t(1;14)(p22;q32) in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. BCL10 contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB.