CAPG Antibody 11 Publications

Rabbit Polyclonal| Catalog number: 10194-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HL-60 cells, mouse heart tissue, mouse thymus tissue, rat heart tissue, rat lung tissue

Positive IP detected in:
mouse heart tissue

Positive IHC detected in:
human prostate cancer tissue, human prostate cancer tissue, human tonsillitis tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
capping protein (actin filament), gelsolin-like

Calculated molecular weight:
39 kDa

Observed molecular weight:
39-42kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CAPG

Synonyms
Actin regulatory protein CAP G, AFCP, CAPG, Macrophage capping protein, MCP
Background

CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.(21908955,22155129)


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