CAPG Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66277-1-Ig |CloneNo.: 3A5B2

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Con: 150 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Jurkat cells, HeLa cells, HL-60 cells

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
capping protein (actin filament), gelsolin-like

Calculated molecular weight:
39 kDa

Observed molecular weight:
39-40 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CAPG

Synonyms
Actin regulatory protein CAP G, AFCP, CAPG, Macrophage capping protein, MCP
Background

CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.(21908955,22155129)


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