CAPG-Specific Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 19535-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 36 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse lung tissue, mouse kidney tissue, U-937 cells

Positive IHC detected in:
human spleen tissue, human stomach cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
capping protein (actin filament), gelsolin-like

Calculated molecular weight:
39 kDa

Observed molecular weight:
43kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CAPG

Synonyms
Actin regulatory protein CAP G, AFCP, CAPG, Macrophage capping protein, MCP
Background

CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.(21908955,22155129)


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