Cyclin D2 Antibody 12 Publications

Rabbit Polyclonal| Catalog number: 10934-1-AP

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human, mouse, pig

Positive WB detected in:
NIH/3T3 cells, MCF-7 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cyclin D2

Calculated molecular weight:
32 kDa

Observed molecular weight:
34 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CCND2

Synonyms
CCND2, cyclin D2, G1/S-specific cyclin-D2
Background

CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. CCND2 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of CCND2 was observed in ovarian and testicular tumors.


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