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hCG Beta Polyclonal antibody

hCG Beta Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 11615-1-AP

Synonyms

CG beta, CGB, CGB3, CGB5, CGB7, CGB8, hCG, hCGB



Tested Applications

Positive IHC detected inhuman placenta tissue, human breast cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11615-1-AP targets hCG Beta in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen hCG Beta fusion protein Ag2191
Full Name CG beta
Calculated Molecular Weight 165 aa, 18 kDa
GenBank Accession NumberBC022796
Gene Symbol CGB
Gene ID (NCBI) 1082
RRIDAB_2877783
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CGB is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of CG. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Protocols

Product Specific Protocols
IHC protocol for hCG Beta antibody 11615-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIF

EBioMedicine

Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta.

Authors - Fangfang Wang
humanWB

Mol Cell Endocrinol

Activation of G protein-coupled estrogen receptor stimulates placental human chorionic gonadotropin expression through PKA-CREB signaling

Authors - Sizhu Yang
humanWB

Biomolecules

Calnexin Is Involved in Forskolin-Induced Syncytialization in Cytotrophoblast Model BeWo Cells

Authors - Hitomi Matsukawa
humanWB,IF

Mol Hum Reprod

The roles of ADAMDEC1 in trophoblast differentiation during normal pregnancy and preeclampsia.

Authors - Zhuo-Hang Li
humanWB

Placenta

Amphiregulin stimulates human chorionic gonadotropin expression by inducing ERK1/2-mediated ID3 expression in trophoblast cells.

Authors - Lanlan Fang
humanWB

Biol Trace Elem Res

PMID: 28983820

Authors - Mengdi Li
  • KD Validated