CHRNA5 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66363-1-Ig |CloneNo.: 3G8C11

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, mouse, pig

Positive WB detected in:
mouse skeletal muscle tissue, human skeletal muscle tissue, C2C12 cell, pig skeletal muscle tissue, A549 cells

Positive IHC detected in:
human bladder tissue, human stomach tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cholinergic receptor, nicotinic, alpha 5

Calculated molecular weight:
468aa,53 kDa

Observed molecular weight:
53 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CHRNA5

Synonyms
CHRNA5, LNCR2, NACHRA5
Background

Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. Variants in the CHRNA5 gene are associated with nicotine dependence and lung cancer risk.


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