CHRNA7 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21379-1-AP

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Con: 34 μg/150 μl

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Species specificity:
human, rat, mouse

Positive WB detected in:
rat brain tissue,mouse skeletal muscle tissue, MCF-7 cells

Positive IHC detected in:
human brain tissue

Positive FC detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cholinergic receptor, nicotinic, alpha 7

Calculated molecular weight:
502aa,56 kDa

Observed molecular weight:
56 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CHRNA7

Synonyms
CHRNA7, CHRNA7 2, NACHRA7
Background

Nicotinic acetylcholine receptors (nAChRs) are cholinergic receptors that form ligand-gated ion channels that mediate fast signal transmission at synapses. CHRNA7 (neuronal acetylcholine receptor subunit alpha-7) forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin.


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