CIDEC Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12287-1-AP

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Freight/Packing

Con: 47 μg/150 μl

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Species specificity:
human

Positive WB detected in:
MCF-7 cells, HeLa cells, L02 cells, MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cell death-inducing DFFA-like effector c

Calculated molecular weight:
238aa,27 kDa

Observed molecular weight:
29 kDa; 48 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CIDEC

Synonyms
Cell death activator CIDE 3, CIDE 3, CIDEC, FLJ20871, Fsp27
Background

Cell death-inducing DFF45-like effector (CIDE) proteins, including Cidea, Cideb and Cidec (also called Fsp27 in rodents), are predominantly expressed in brown adipose tissues (BAT), liver and WAT. Recent studies found that overexpression of Fsp27 induces the accumulation of lipid droplets (LDs) and enhances LD size; knockdown of Fsp27 decreases LD size and increases LD number in 3T3-L1 adipocytes. Cidec is localized on the surface of lipid droplets and could promote the differentiation of human adipocytes. Catalog#12287-1-AP recognizing CIDEC (calculated 28 kDa) as a 30 kDa and 45-50 kDa due to its posttranslational modification (PMID: 19258494).


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