CLTB Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66270-1-Ig |CloneNo.: 1F9C2

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Freight/Packing

Con: 198 μg/150 μl

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Species specificity:
human, pig

Positive WB detected in:
pig brain tissue

Positive IHC detected in:
human liver tissue, human kidney tissue, human liver tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
clathrin, light chain (Lcb)

Calculated molecular weight:
23 kDa

Observed molecular weight:
32-38 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CLTB

Synonyms
Clathrin light chain B, clathrin, light chain (Lcb), CLTB, LCB
Background

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. The clathrin molecule has a triskelion shape. Each clathrin triskelion is composed of three identical heavy chains (180 kDa) and three light chains of two types, LCA (CLTA) and LCB (CLTB) (30-40 kDa). The light chain subunits are thought to regulate the formation or disassembly of clathrin coats. (PMID: 2445759; 8374173; 3563513)


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