Collagen Type IV Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 19797-1-AP

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Freight/Packing

Con: 25 μg/150 μl

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Tested Applications

Applications:
ELISA, IF, WB
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
collagen, type IV, alpha 5

Calculated molecular weight:
161 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
COL4A5

Synonyms
ASLN, ATS, CA54, COL4A5, Collagen alpha 5(IV) chain, Collagen Type IV, collagen, type IV, alpha 5
Background

COL4A5 belongs to the type IV collagen family. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Defects in COL4A5 are the cause of Alport syndrome X-linked (APSX). Deletions covering the N-terminal regions of COL4A5 and COL4A6, which are localized in a head-to-head manner, are the cause of diffuse leiomyomatosis with Alport syndrome (DL-ATS)which also known as esophageal and vulval leiomyomatosis with nephropathy or Alport syndrome and diffuse leiomyomatosis (ATS-DL).


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