COX7C Polyclonal antibody

COX7C Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 11411-2-AP

Synonyms

COX7C



Tested Applications

Positive WB detected inmouse ovary tissue, human skeletal muscle tissue
Positive IHC detected inhuman gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inMCF-7 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11411-2-AP targets COX7C in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen COX7C fusion protein Ag1989
Full Name cytochrome c oxidase subunit VIIc
Calculated Molecular Weight 63 aa, 7 kDa
Observed Molecular Weight 15~28 kDa
GenBank Accession NumberBC007498
Gene Symbol COX7C
Gene ID (NCBI) 1350
RRIDAB_2085713
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

COX7C(Cytochrome c oxidase subunit 7C, mitochondrial) is the terminal enzyme in the mitochondrial respiratory chain (oxidative phosphorylation OXPHOS), catalyzing the elctron transfer from reduced cytochrome c to molecule oxygen. This protein belongs to the cytochrome c oxidase VIIc family. The full length protein has a transit peptide with 16 amino acids. This antibody is specific to COX7C.

Protocols

Product Specific Protocols
WB protocol for COX7C antibody 11411-2-APDownload protocol
IHC protocol for COX7C antibody 11411-2-APDownload protocol
IF protocol for COX7C antibody 11411-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Cell Death Dis

O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma.

Authors - Weicheng Wu
humanWB

J Biol Chem

PMID: 20870728

Authors - Oliva Claudia R CR
humanWB

Cancer Sci

Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.

Authors - Lianqin Liu
humanIF

J Neuropathol Exp Neurol

Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease.

Authors - Belén Ansoleaga
mouseWB,IF

Front Pharmacol

Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury

Authors - Jingjing Jia
  • KD Validated
mouseWB

Nat Commun

ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury

Authors - Yankun Zhang