CTBP1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10972-1-AP

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Freight/Packing

Con: 25 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
Jurkat cells, HeLa cells, HL-60 cells, mouse brain tissue, mouse skeletal muscle tissue, mouse thymus tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human prostate cancer tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
C-terminal binding protein 1

Calculated molecular weight:
48 kDa

Observed molecular weight:
48 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CTBP1

Synonyms
BARS, C terminal binding protein 1, CTBP, CTBP1
Background

CTBP1, also named as C-terminal-binding protein 1, is a 440 amino acid protein, which belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. CTBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CTBP1 and the related protein CTBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CTBP1 is expressed from embryo to adult, but CTBP2 is mainly expressed during embryogenesis.


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