CXCR4 Polyclonal antibody
CXCR4 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
Cat no : 16162-1-AP
Synonyms
Validation Data Gallery
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
16162-1-AP targets CXCR4 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide |
| Full Name | chemokine (C-X-C motif) receptor 4 |
| Calculated Molecular Weight | 40 kDa |
| GenBank Accession Number | NM_001008540 |
| Gene Symbol | CXCR4 |
| Gene ID (NCBI) | 7852 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
The chemokine receptor CXCR4, a 7-transmembrane protein on cell surface, acts with the CD4 protein to support HIV entry into cells. CXCR4 is highly expressed in brain and heart, white blood cells, vascular endothelial cells, and umbilical cord endothelial cells. Lots of CXCR4 isoforms have been reported: 47, 50, 62, and 98-102 kDa. The 62-kDa CXCR4 is predominantly ubiquitinated and6 preferentially associated with CD4.
