Cardiac Troponin I Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66376-1-Ig |CloneNo.: 1D5D6

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Con: 150 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human heart tissue, mouse heart tissue

Positive IHC detected in:
human heart tissue

Positive IF detected in:
mouse heart tissue

Recommended dilution:
WB : 1:5000-1:50000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
troponin I type 3 (cardiac)

Calculated molecular weight:
210aa,24 kDa

Observed molecular weight:
26-28 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TNNI3

Synonyms
Cardiac troponin I, CMD2A, CMH7, cTnI, RCM1, TNNC1, TNNI3, troponin I type 3 (cardiac), Troponin I, cardiac muscle
Background

Troponin I (TnI) is the inhibitory subunit of troponin, the structural protein involved in the regulation of striated muscle contraction. Cardiac Troponin I (cTnI) is produced by cardiac muscle. Two other TnI isoforms (slow sTnI and fast sTnI) are produced by slow-twitch and fast-twitch skeletal muscles, respectively. cTnI has been considered as one of the most specific and sensitive markers of myocardial damage like acute myocardial infarction (AMI) for decades. Detection of cTnI in serum is widely accepted as a diagnostic tool in acute coronary syndromes. This antibody is specific to cTnI, but not cross-react with skeletal TnI.


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