p150 glued Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55182-1-AP

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Freight/Packing

Con: 25 μg/150 μl

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Species specificity:
human, mouse, rat, dog

Positive WB detected in:
human brain tissue, human brain tissue, Jurkat cells

Positive IHC detected in:
human brain tissue

Positive IF detected in:
MDCK cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
dynactin 1 (p150, glued homolog, Drosophila)

Calculated molecular weight:
142 kDa

Observed molecular weight:
135 kDa,150 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DCTN1

Synonyms
DAP 150, DCTN1, DP 150, Dynactin subunit 1, HMN7B, P135, p150 glued
Background

DCTN1, also named as DAP-150, p150-glued and p135, belongs to the dynactin 150 kDa subunit family. It is required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. Defects in DCTN1 are the cause of distal hereditary motor neuronopathy type 7B (HMN7B). This antibody is specific to DCTN1.


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