DDR2 Monoclonal antibody

DDR2 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human and More (1)

Applications

WB, IF, ELISA

Conjugate

Unconjugated

CloneNo.

1E9A10

Cat no : 67126-1-Ig

Synonyms

DDR2, Discoidin domain receptor 2, MIG20a, NTRKR3, TKT, TYRO10, Tyrosine protein kinase TYRO10



Tested Applications

Positive WB detected inJurkat cells, HEK-293 cells, HepG2 cells, HeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

67126-1-Ig targets DDR2 in WB, IF, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivityhuman
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen DDR2 fusion protein Ag28340
Full Name discoidin domain receptor tyrosine kinase 2
Calculated Molecular Weight 97 kDa
Observed Molecular Weight 100-110 kDa
GenBank Accession NumberNM_001014796
Gene Symbol DDR2
Gene ID (NCBI) 4921
RRIDAB_2882426
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DDR2 (Discoidin domain receptor 2) belongs to the receptor tyrosine kinase (RTK) family and is activated by collagen-binding.DDR2 is implicated in several physiological and pathological processes, including wound healing, angiogenesis, ovulation, spermatogenesis, extracellular matrix (ECM) remodeling and fibrosis, and tumor progression (PMID: 25805889). Moreover, DDR2 is prominently present in the fibroblasts, smooth muscle cells, myofibroblasts, and chondrocytes (PMID: 37834343).

Protocols

Product Specific Protocols
WB protocol for DDR2 antibody 67126-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIF

J Cell Mol Med

The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.

Authors - Ke Xue
humanWB

Int J Biol Macromol

Human type III collagen-derived biomaterial with high antitumor activity inhibits breast cancer cell autophagy, proliferation, and migration through DDR1

Authors - Xiaowei Liu