DDX4,VASA Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12888-1-AP

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Freight/Packing

Con: 17 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4

Calculated molecular weight:
690aa,76 kDa;724aa,79 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DDX4

Synonyms
DDX4, DEAD box protein 4, VASA, Vasa homolog
Background

DEAD box proteins are characterized by nine conserved sequence motifs located on two functional domains. Domain I contains six of these motifs, including the Q motif and the Walker A motif, motifs Ia and Ib, the Walker B motif, and motif III, which may act to link ATPase and helicase activities of the protein [PMID:21653890]. DDX4, a member of the DEAD box family of ATP-dependent RNA helicases, plays a central role in several aspects of germ cell development. Its function is not only required during gametogenesis in the adult but is also essential for the specification of the germ cell lineage during embryogenesis [PMID:20016130].


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