Desmin Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 16520-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse heart tissue, human heart tissue, mouse heart tissue, mouse skeletal muscle tissue, rat heart tissue

Positive IP detected in:
mouse heart tissue

Positive IHC detected in:
human heart tissue, human appendix tissue, human colon tissue, human heart tissue, human hysteromyoma tissue, human placenta tissue, human skeletal muscle tissue, human testis tissue, rat heart tissue

Positive IF detected in:
C2C12 cell

Positive FC detected in:
C2C12 cell

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:1000-1:6000 for WB
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
desmin

Calculated molecular weight:
470aa,54 kDa

Observed molecular weight:
52-53 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DES

Synonyms
CMD1I, CSM1, CSM2, DES, desmin, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Background

Desmin is the main intermediate filament protein in skeletal and cardiac muscle cells and is essential for both the structural integrity and the survival of muscle cells. As an abundant muscle-specific protein, desmin has been widely used as a marker of muscle derived tumors. Anti-desmin is also valuable in the differential diagnosis of tumors of uncertain origin.


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