E2F4 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10923-1-AP

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, HL-60 cells, Jurkat cells, NIH/3T3 cells, Raji cells

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human lymphoma tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
E2F transcription factor 4, p107/p130-binding

Calculated molecular weight:
44 kDa

Observed molecular weight:
60-70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
E2F4

Synonyms
E2F 4, E2F4, Transcription factor E2F4
Background

Transcription factor E2F4 (E2F4) is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein..The observed molecular weight of 60-70 kDa is the phosphorylation of E2F4 protein.


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