Endothelin 1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 12191-1-AP

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Con: 28 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
NIH/3T3 cells, human ileum tissue, SGC-7901 cells

Positive IHC detected in:
human lung cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
endothelin 1

Calculated molecular weight:
212aa,24 kDa

Observed molecular weight:
24 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EDN1

Synonyms
EDN1, endothelin 1, ET 1 Big endothelin 1, ET1, HDLCQ7, PPET1, Preproendothelin 1
Background

EDN1, also named as Endothelin-1, PPET1 and ET-1, belongs to the endothelin/sarafotoxin family. Endothelins are endothelium-derived vasoconstrictor peptides. Emerging basic science, and animal and human data all suggest that EDN1 is a potentially important contributor in the pathobiology of fibrosing disorders, including those that affect the lung(PMID:20055532 ).


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