EEF1B2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60329-1-Ig |CloneNo.: 3E1C11

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HEK-293 cells, HeLa cells

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:1000-1:4000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
eukaryotic translation elongation factor 1 beta 2

Calculated molecular weight:
25 kDa

Observed molecular weight:
30-34 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EEF1B2

Synonyms
EEF1B, EEF1B1, EEF1B2, EF 1 beta, EF1B, Elongation factor 1 beta
Background

In eukaryotes, the translation elongation factor eEF1A responsible for transporting amino-acylated tRNA to the ribosome forms a higher-order complex, eEF1H, with its guanine-nucleotide-exchange factor eEF1B. eEF1B consists of three subunits: eEF1B alpha, eEF1B beta and eEF1B gamma. The eEF1B2 possess the nucleotide-exchange activity. Although several models on the basis of in vitro experiments have been proposed for the macromolecular organization of the eEF1H complex, these models differ in various aspects. The human eukaryote elongation factor 1 beta 2 (eEF1B2) migrated as a 30-34 kDa protein in SDS-PAGE.


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