EGFR (N-terminal) Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 22542-1-AP

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Freight/Packing

Con: 41 μg/150 μl

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Tested Applications

Applications:
ELISA, IHC
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Species specificity:
human

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)

Calculated molecular weight:
1210aa,134 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EGFR

Synonyms
EGFR, ERBB, ERBB1, HER1, mENA, PIG61, Proto oncogene c ErbB 1
Background

ERBB1, also mamed as EGFR, is a receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. ERBB1 is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with C-SRC and CTNNB1/beta-catenin. Isoform 2/truncated isoform of ERBB1 may act as an antagonist. EGFR is associated with lung cancer. The antibody can recognize all the isoforms.


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