EIF3M Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66025-1-Ig |CloneNo.: 2A12B2

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Freight/Packing

Con: 102 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Hela cells, HepG2 cells, MCF-7 cells

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:10-1:100

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
eukaryotic translation initiation factor 3, subunit M

Calculated molecular weight:
374aa,43 kDa

Observed molecular weight:
43kD

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EIF3M

Synonyms
B5, EIF3M, Fetal lung protein B5, FLJ29030, GA17, hfl B5, HFLB5, PCID1, PNAS 125
Background

EIF3M gene encodes eukaryotic translation initiation factor (eIF) subunit M, also called GA17 or PCID1. eIF-3 complex is required for several steps in the initiation of protein synthesis, and recent studies indicate that regulation of oncogene expression and neoplastic transformation are controlled by eIF subunits. The most uncharacterized non-core subunit EIF3M was confirmed to be highly expressed in human cancer cell lines and colon cancer patient tissues and mediate regulation of tumorigenesis-related genes in human colon cancer.


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