EPHA1-specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18698-1-AP

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Freight/Packing

Con: 25 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
A549 cells, HeLa cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human liver cancer tissue

Positive IF detected in:
A549 cells

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
EPH receptor A1

Calculated molecular weight:
108 kDa

Observed molecular weight:
150 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EPHA1

Synonyms
EPH, EPH receptor A1, EPHA1, Ephrin type A receptor 1, EPHT, EPHT1
Background

EPHA1, also named as EPH, EPHT and EPHT1, belongs to ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Ligands in the ephrin-A subclass, including the prototype family member ephrin-A1 (B61), are membrane associated through glycosylphosphatidyl-inositol linkages, whereas ephrin-B subclass consists of ligands with transmembrane domains. The general role of the Eph family is in mediating repulsive cell-cell interaction.


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