ERCC1 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66275-1-Ig |CloneNo.: 1H4D5

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human

Positive WB detected in:
A431 cells

Positive IF detected in:
A431 cells

Recommended dilution:
WB : 1:1000-1:4000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

Calculated molecular weight:
33 kDa

Observed molecular weight:
38 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ERCC1

Synonyms
COFS4, ERCC1, UV20
Background

Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11, XPF and ERCC4, which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1, together with RRM1, are determinants of survival after surgical treatment of early-stage, non-small-cell lung cancer. (Ref: Simon, ER. 2005)


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