EWS Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55191-1-AP

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Freight/Packing

Con: 86 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells, human testis tissue, K-562 cells, mouse testis tissue

Positive IHC detected in:
human colon cancer tissue, human small intestine tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
Ewing sarcoma breakpoint region 1

Calculated molecular weight:
68 kDa

Observed molecular weight:
90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
EWSR1

Synonyms
EWS, EWS oncogene, EWSR1, RNA binding protein EWS
Background

EWS, also named as WSR1, belongs to the RRM TET family. It might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. This antibody is specific to EWS.


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