FAK Antibody 15 Publications

Rabbit Polyclonal| Catalog number: 12636-1-AP

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Freight/Packing

Con: 80 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
MCF7 cells, A431 cells, HEK-293 cells, HeLa cells, Jurkat cells, MCF-7 cells, NIH/3T3 cells

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human gliomas tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
PTK2 protein tyrosine kinase 2

Calculated molecular weight:
1052aa,119 kDa

Observed molecular weight:
110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PTK2

Synonyms
FADK, FADK 1, FAK, FAK1, Focal adhesion kinase 1, pp125FAK, Protein tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2
Background

FAK (Focal adhesion kinase 1) is also named as FAK1, FADK, pp125FAK, FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion, migration, proliferation and survival in response to extracellular signals (PMID:19664602). It also acts as a pivotal signal 'integrator', controlling and coordinating cellular responses that include cell migration, survival, proliferation and, epithelial tissue repair after DNA damage (PMID:20966971). This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.


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