FOXP3 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60149-1-Ig |CloneNo.: 7B6A8

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Freight/Packing

Con: 36 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse, rat, monkey

Recommended dilution:

Product Information


Source:
Mouse

Purification method:
Caprylic acid/ammonium sulfate precipitation

Isotype:
IgM

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
peptide

Full name:
forkhead box P3

Calculated molecular weight:
47 kDa

Observed molecular weight:
48 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FOXP3

Synonyms
AIID, DIETER, forkhead box P3, Forkhead box protein P3, FOXP3, IPEX, JM2, PIDX, Scurfin, XPID
Background

FOXP3, also named as IPEX, JM2 and Scurfin, is a transcription factor. POXP3 plays a critical role in the control of immune response. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX)]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human FOXP3.


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