FOXP3 Monoclonal antibody
FOXP3 Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgM
Reactivity
human, mouse, rat, monkey
Applications
IF, ELISA
Conjugate
Unconjugated
CloneNo.
7B6A8
Cat no : 60149-1-Ig
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Published Applications
IF | See 1 publications below |
Product Information
60149-1-Ig targets FOXP3 in IF, ELISA applications and shows reactivity with human, mouse, rat, monkey samples.
Tested Reactivity | human, mouse, rat, monkey |
Cited Reactivity | human |
Host / Isotype | Mouse / IgM |
Class | Monoclonal |
Type | Antibody |
Immunogen | peptide |
Full Name | forkhead box P3 |
Calculated Molecular Weight | 47 kDa |
Observed Molecular Weight | 48 kDa |
GenBank Accession Number | NM_014009 |
Gene Symbol | FOXP3 |
Gene ID (NCBI) | 50943 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Caprylic acid/ammonium sulfate precipitation |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
FOXP3, also named as IPEX, JM2 and Scurfin, is a transcription factor. POXP3 plays a critical role in the control of immune response. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX)]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human FOXP3.
Publications
Species | Application | Title |
---|---|---|
Thorac Cancer Potential activity of adiponectin-expressing regulatory T cells against triple-negative breast cancer cells through the cell-in-cell phenomenon |