FOXP3 Monoclonal antibody

FOXP3 Monoclonal Antibody for ELISA

Host / Isotype

Mouse / IgM

Reactivity

human, mouse, rat, monkey

Applications

IF, ELISA

Conjugate

Unconjugated

CloneNo.

7B6A8

Cat no : 60149-1-Ig

Synonyms



Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

IFSee 1 publications below

Product Information

60149-1-Ig targets FOXP3 in IF, ELISA applications and shows reactivity with human, mouse, rat, monkey samples.

Tested Reactivity human, mouse, rat, monkey
Cited Reactivityhuman
Host / Isotype Mouse / IgM
Class Monoclonal
Type Antibody
Immunogen peptide
Full Name forkhead box P3
Calculated Molecular Weight 47 kDa
Observed Molecular Weight 48 kDa
GenBank Accession NumberNM_014009
Gene Symbol FOXP3
Gene ID (NCBI) 50943
Conjugate Unconjugated
Form Liquid
Purification MethodCaprylic acid/ammonium sulfate precipitation
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FOXP3, also named as IPEX, JM2 and Scurfin, is a transcription factor. POXP3 plays a critical role in the control of immune response. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX)]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human FOXP3.

Publications

SpeciesApplicationTitle
humanIF

Thorac Cancer

Potential activity of adiponectin-expressing regulatory T cells against triple-negative breast cancer cells through the cell-in-cell phenomenon

Authors - Wakana Chikaishi