Fascin Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66321-1-Ig |CloneNo.: 1B5G3

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human

Positive WB detected in:
SH-SY5Y cells, HeLa cells, K-562 cells

Positive IHC detected in:
human tonsillitis tissue, human pancreas cancer tissue, human skin cancer tissue, human tonsillitis tissue

Positive IF detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:20-1:2000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

Calculated molecular weight:
55 kDa

Observed molecular weight:
55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FSCN1

Synonyms
55 kDa actin bundling protein, FAN1, Fascin, Fascin 1,Fascin, FLJ38511, FSCN1, HSN, p55, Singed like protein, SNL
Background

Fascin is a highly conserved and ubiquitous actin cross-linking protein that has a major function in cell motility and adhesion. Fascin localizes to a number of highly dynamic cellular structures that require strong mechanical support which include stress fibers and cellular protrusions such as microvilli, microspikes and lamellipodia. Fascin is up-regulated in many human carcinomas. It’s a marker for Reed-Sternberg cells in Hodgkin's disease; it is also a highly selective marker for dendritic cells of lymphoid tissues.


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