GDI2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55096-1-AP

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Con: 20 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HepG2 cells

Positive IHC detected in:
human skin, human liver tissue, human skin tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
GDP dissociation inhibitor 2

Calculated molecular weight:
51 kDa

Observed molecular weight:
46-50kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GDI2

Synonyms
GDI2, Rab GDI beta, FLJ37352, RABGDIB, FLJ16452
Background

GDP dissociation inhibitors (GDIs) are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, GDIs can bind and release GDP-bound Rab proteins from membranes. Two GDI proteins towards different Rab proteins have been identified. GDI1 interacts with almost all of the Rab proteins, while GDI2 interacts with Rabll but not Rab3A. GDI2 distributes ubiquitously, displaying a membrane bound location in perinuclear regions of cells. GDI-2 was thought to be involved in cellular response to insulin. It electrophoreses as a 46kd protein in SDS-PAGE. (PMID: 7929030; PMID: 19570034). The antibody is specific to GDI2. And it has no cross reaction to GDI1.


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