Alpha galactosidase A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 15428-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 24 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HEK-293 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human liver cancer tissue, human liver tissue, human liver cancer tissue, mouse liver tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:100-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
galactosidase, alpha

Calculated molecular weight:
49 kDa

Observed molecular weight:
49 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GLA

Synonyms
Alpha galactosidase A, galactosidase, alpha
Background

GLA, also named as Melibiase, Agalsidas and Alpha-galactosidase A, Belongs to the glycosyl hydrolase 27 family. It hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. Fabry disease is an X-linked lysosomal storage disorder resulting from the deficient activity of GLA. Enzyme replacement therapy (ERT) with GLA is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease.


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