GLRA1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17951-1-AP

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Freight/Packing

Con: 50 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, mouse brain tissue, mouse cerebellum tissue, SH-SY5Y cells

Positive FC detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:3000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glycine receptor, alpha 1

Calculated molecular weight:
449aa,52 kDa

Observed molecular weight:
48 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GLRA1

Synonyms
GLRA1, glycine receptor, alpha 1, STHE
Background

Glycine is an inhibitory neurotransmitter in the central nervous system. The glycine receptor (GlyR) is a member of the nicotinic acetylcholine receptor of ligand-gated ion channels. This receptor has important roles in a variety of physiological processes, especially in mediating inhibitory neurotransmission in the spinal cord and brain stem. GlyR is a pentameric receptor comprised of alpha and beta subunits. Four alpha-subunits (GLRA1, GLRA2, GLRA3, GLRA4) and one beta-subunit (GLRB) of GlyR have been identified. (PMID: 11409700; 15383648)


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