GLRX3 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 11254-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, Jurkat cells

Positive IHC detected in:
human colon cancer tissue, human ovary tumor tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glutaredoxin 3

Calculated molecular weight:
37 kDa

Observed molecular weight:
37kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GLRX3

Synonyms
bA500G10.4, FLJ11864, GLRX3, GLRX4, Glutaredoxin 3, GRX3, GRX4, PICOT, PKC theta interacting protein, PKCq interacting protein, Thioredoxin like protein 2, TXNL2, TXNL3
Background

GLRX3(Glutaredoxin-3) is also named as PICOT, TXNL2. Mammalian glutaredoxin 3 is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals(PMID:20226171). Glrx3 could take a pivotal role in colon and lung cancer cells during the tumorigenesis, which is expressed in lung and colon cancers consistently and preferentially(PMID:19797004).


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