GUCY2C Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 23011-1-AP

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Con: 0 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
guanylate cyclase 2C (heat stable enterotoxin receptor)

Calculated molecular weight:
1073aa,123 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GUCY2C

Synonyms
GUCY2C, Intestinal guanylate cyclase, hSTAR, GUC2C, Guanylyl cyclase C
Background

GUCY2C is also named as GUC2C, STAR(Heat-stable enterotoxin receptor), Guanylyl cyclase C and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the E.coli heat-stable enterotoxin and considered to be the true apical membrane receptor for the endogenous ligands uroguanylin and guanylin. GUCY2C is not present in the endocrine pancreas, but is localized exclusively to the ductal system which fully corresponds to the GUCY2C activity detected in the exocrine ductal system, but particularly not in islets of Langerhans. GUCY2C with a molecular mass of 130 kDa is detected in pancreatic and intestinal extracts.(PMID:11431160). The full length protein is 123 kDa and has a signal peptide and nine glycosylation sites. This antibody is specific to GUCY2C.


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