Granzyme A Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 11288-1-AP

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Con: 26 μg/150 μl

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Species specificity:
human, mouse, chicken

Positive WB detected in:
Jurkat cells, mouse kidney tissue

Positive IHC detected in:
human lymphoma tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

Calculated molecular weight:
29 kDa

Observed molecular weight:
60kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GZMA

Synonyms
CTL tryptase, CTLA3, Fragmentin 1, Granzyme 1, Granzyme A, GZMA, H factor, Hanukkah factor, HF, HFSP
Background

Granzyme A is necessary for target cell lysis in cell-mediated immune responses. It activates mitochondrial outer membrane permeabilization- and caspase-independent cell death pathways by cleaving the mitochondrial complex I component NDUFS3after lys56. This protein has 2 isoforms produced by alternative promoter usage.


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