HDAC4-specific Monoclonal antibody

HDAC4-specific Monoclonal Antibody for ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

ELISA

Conjugate

Unconjugated

CloneNo.

4C3B9

Cat no : 60105-1-Ig

Synonyms



Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

60105-1-Ig targets HDAC4-specific in ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen peptide
Full Name histone deacetylase 4
Calculated Molecular Weight 119 kDa
GenBank Accession NumberBC039904
Gene Symbol HDAC4
Gene ID (NCBI) 9759
Conjugate Unconjugated
Form Liquid
Purification MethodCaprylic Acid/Ammonium Sulfate Precipitation
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

HDAC4, also named as HDACA, belongs to the histone deacetylase family. HDAC4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human HDAC4.

Publications

SpeciesApplicationTitle

Genes Dev

MEF2 transcription factors are key regulators of sprouting angiogenesis.

Authors - Natalia Sacilotto