HEXIM1 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66311-1-Ig |CloneNo.: 2C8A2

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Con: 45 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human testis tissue, MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Mouse

Purification method:
Thiophilic affinity chromatograph

Isotype:
IgM

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
hexamethylene bis-acetamide inducible 1

Calculated molecular weight:
41 kDa

Observed molecular weight:
54 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HEXIM1

Synonyms
Cardiac lineage protein 1, CLP1, EDG1, FLJ13562, HEXIM1, HIS1, MAQ1, Menage a quatre protein 1, Protein HEXIM1
Background

HEXIM1, also named CLP1, EDG1, HIS1 or MAQ1, is best known as the inhibitor of positive transcription elongation factor b, which regulates the transcription elongation of RNA polymerase II and controls 60-70% of mRNA synthesis. HEXIM1 regulates NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Previous studies showed that HEXIM1 interacts with two key p53 regulators, nucleophosmin and HDM2, implying a possible connection between HEXIM1 and the p53 signaling pathway.The mainstream MW of this protein is 70 and 54 kDa. Catalog#66311-1-Ig recognises 54 kDa band.


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